Famvir Drug Uses

Famvir is an oral antiviral prescription medication that is prescribed for: treatment of recurrent genital herpes in otherwise healthy patients; suppression of recurrent genital herpes in otherwise healthy patients; treatment of recurrent herpes simplex virus infections (genital herpes and cold sores) in HIV-infected patients and herpes zoster (shingles).

How Taken

Famvir can be prescribed in one of three ways:
-Episodic treatment: your doctor treats an outbreak of genital herpes as it occurs. The usual dose of Famvir is one 125-mg pill, twice a day, for 5 days.
-Suppressive treatment: if you have frequent or severe outbreaks, you take one 250-mg pill, twice a day, for up to 1 year to suppress the genital herpes virus and help to prevent outbreaks.
-Patients with HIV: Famvir is the only prescription oral antiviral therapy indicated for treating genital. In patients with herpes simplex and HIV, the dose of Famvir is 500 mg, twice a day, for 7 days.
Famvir can be taken with or without food.

Famvir Warnings/Precautions

Do not take Famvir if you are allergic to penciclovir (Denavir) without first talking to your doctor. Before taking this medication, tell your doctor if you have kidney disease. You may need a dosage adjustment or special monitoring during treatment with Famvir. Famvir (Pregnancy Category B) should be used during pregnancy only if the benefit to the patient clearly exceeds the risk to the fetus.

Famvir Missed Dose

IF YOU MISS A DOSE OF THIS MEDICINE, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do NOT take 2 doses at once.

Famvir Possible Side Effects

Stop taking Famvir and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives). Other, less serious side effects may be more likely to occur. Continue to take Famvir and talk to your doctor if you experience nausea or vomiting, a headache, diarrhea, dizziness, tingling in your hands or feet, or itching.

Famvir Storage

Store between 15C and 30C (59F and 86F) and out of reach of children.

Famvir Overdose

Seek emergency medical attention. A Famvir overdose has no known symptoms, but an overdose of acyclovir (Zovirax), which is a similar drug, may cause seizures, hallucinations, and kidney damage (decreased urine production).

More Information

Treatment with Famvir should be started as soon as possible after the first appearance of symptoms (e.g. tingling, burning, blisters). Take all of the Famvir that has been prescribed for you even if you begin to feel better. Your symptoms may start to improve before the infection is completely treated. Herpes infections are contagious and you can infect other people, even during treatment. Avoid letting infected areas come into contact with other people. Wash your hands frequently to prevent transmission. For more information, talk to your doctor, pharmacist or health care provider.

Disclaimer

This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.

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The FDA has approved the drug Famvir as the first and only one-day antiviral treatment for recurrent genital herpes and cold sores in people with healthy immune systems.
The drug’s maker, Novartis Pharmaceuticals Corp., announced the FDA approval in a news release dated July 28.
At least 45 million people age 12 and older in the U.S. have had a genital herpes infection -- or about one in five in that age range, says the CDC.
Before, genital herpes required five days of Famvir treatment -- although at a lower dose. Famvir was not FDA approved for cold sores in people with healthy immune systems (meaning those without aids).
The new approval shortens Famvir treatment to a single day at the start of an outbreak and adds cold sores to the drug’s approved uses.
What’s Your Risk for Genital Herpes?
Famvir Dosage
Patients would take 1,000 milligrams of Famvir twice daily for one day at the first sign of genital herpes symptoms, and 1,500 milligrams of Famvir once for one day at the first sign of cold sore symptoms to shorten outbreaks and reduce symptoms.
The drug, available only by prescription, is taken orally.
It does not cure genital herpes or cold sores. Currently, there is no cure for herpes. Antiviral drugs such as Famvir, Zovirax and Valtrex can only help treat or suppress the infection.
Famvir earned FDA approval in 1994 and is used to treat shingles, as well as the herpes virus which causes both genital herpes and cold sores.
Vaginal Gel Blocks HIV, Herpes
Timing Counts
Single-day Famvir should be started within six hours of the first sign of symptoms, such as tingling, itching, burning, or the appearance of herpes sores, says Novartis.
There is “a narrow window of opportunity for treatment” at the start of an outbreak of herpes or cold sores, says Novartis.
Timing is crucial because the virus copies itself most actively in an outbreak’s first hours. Interrupting that process may shorten the outbreak and reduce its severity.
Get the Facts on Sexually Transmitted Diseases
Herpes Virus
There are two types of the herpes simplex virus: herpes simplex virus 1 (HSV-1) and herpes simplex virus 2 (HSV-2).
Cold sores are typically caused by the former, which can spread by kissing an infected person or sharing eating utensils, towels, or razors.
Genital herpes is a sexually transmitted disease (STD) and is usually caused by HSV-2, although it can result from HSV-1.
Most genital herpes patients have few or no symptoms, the CDC notes.
When symptoms appear, there are usually one or more blisters around the genitals or rectum. The blisters can break, leaving tender sores that may take several weeks to heal.
Clinical Trials
Single-day Famvir was tested in clinical trials for treatment of recurrent genital herpes and cold sores.
The genital herpes trial included 329 patients. At the first sign of a herpes outbreak, they got one of two treatments, without knowing which they received:
1,000 milligrams of Famvir twice daily for one day A pill containing no medicine (placebo).
The Famvir group had milder symptoms and shorter outbreaks that lasted about four days, instead of six days with the placebo, Novartis reports.
Single-dose Famvir had a similar effect on the length and severity of cold sores in the cold sores trial, which included 481 patients, according to Novartis.
Novartis is a WebMD sponsor.

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